POSITION AVAILABLE:
NMR STRUCTURE DETERMINATION OF CATALYTIC HAEM PROTEINS
As part of the European Union TMR Research Network 'Haemworks', a grant
is available at the Leiden Institute of Chemistry, Leiden University,
the Netherlands, for a
postdoctoral researcher or graduate student
The Network involves the Universities of Leiden, Florence, Lisbon,
Seville, and Southampton, and the researcher will participate in the
part of the project which is aimed at the creation of small, stable
enzymes with peroxidase or monooxygenase activity. This is achieved by
protein engineering of a bacterial haem protein, cytochrome c-550. For a
proper understanding of the factors that influence the catalytic
properties of these new proteins, detailed structures of the proteins
and, in particular, the active sites, are essential. The dynamics of the
protein variants also need to be established in depth. The researcher
will focus on the elucidation of these topics by NMR.
Candidates have to be a citizen of a member state (or associated state)
of the European Union. Experience with NMR on biomolecules and/or with
protein biochemistry is an advantage.
The grant is for one year with the possibility of an extension. Monthly
pay in the DFL 2 500 - 3 500 range depending on qualifications and
experience. The position is available as per May 1st, 1998.
Further information can be obtained from
Dr M. Ubbink (until 29 May)
tel -31 71 527 4628
e-mail: m.ubbink at chem.leidenuniv.nl
or
Prof. Dr G. W. Canters (after 29 May)
tel -31 71 527 4256
e-mail: canters at chem.leidenuniv.nl
and from http://www.cordis.lu/tmr/src/lifvacls.htm
Applications together with CV, list of publications and names of 2
professional referees to be sent within 3 weeks to:
Prof. Dr G.W. Canters
Leiden Institute of Chemistry
PO Box 9502
2300 RA Leiden, The Netherlands.
