PDF in protein crystallography

Mirek Cygler Mirek.Cygler at BRI.NRC.CA
Mon Nov 15 18:32:23 EST 1999


       Post-doctoral position is available in the Macromolecular Structure
Group at the Biotechnology Research Institute, NRC, Montreal, Canada.
The Group is part of the Montreal Joint Centre for Structural Biology, a
consortium of universities, BRI and industrial partners in the Montreal
area. The research activities of the group focus on structural
characterization of proteins by crystallography to gain detailed
understanding of their mode of action. The successful applicant would
participate in the pilot project in structural genomics with the main
responsibilities in the area of protein purification, crystallization and
structure determination. Involvement with bioinformatics aspects of the
project, including target selection and analysis of the results, will be
     The candidate is expected to have a Ph.D. degree in biochemistry,
protein crystallography or chemistry. Previous experience in a protein
crystallography or bioinformatics laboratory is an important asset. Some
experience in protein purification is required. Our laboratory is very well
equipped for all aspects of structural work. There are area detectors, a
network of a large number of graphics workstations and servers, very
good facilities for protein purification and crystallization. We have a good
access to the synchrotron beamline. The group includes macromolecular
crystallographers, technicians and a computer specialist. There are many
interactions with the NMR group and computational chemistry groups in
the Institute. BRI provides a challenging environment which promotes
collaborative work within the Institute and outside.
     Montreal is a vibrant, multicultural city with many cultural, social
and recreational activities. Excellent restaurants with variety of ethnic
food, charm of the Old Montreal, famous summer jazz festival, good
cross-country and downhill skiing in the winter within 45 min from the city
and excellent biking paths in the summer. 

     For more information contact:
          Dr. Mirek Cygler
          Biotechnology Research Institute
          6100 Royalmount Avenue
          Montreal, Quebec H4P 2R2
          tel: 514-496-6321
          fax: 514-496-5143
          email: mirek at bri.nrc.ca

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