TENTH ANNUAL ACA SUMMER COURSE IN CRYSTALLOGRAPHY
The tenth annual ACA Summer Course in Crystallography will be a 12 day
course held from June 8 to June 20, 2001 at the University of Georgia,
Athens GA.
The first seven days of the course will be devoted to basic
crystallography
of small molecules and will include lectures on the mathematics and
physics
behind structural analysis, the methods of structure solution, the
refinement of atomic parameters and the presentation and analysis of the
results of a structure determination. The laboratory associated with
this
part of the course will teach students to select and mount small
molecule
crystals, determine their unit cell dimensions and collect data on
modern
equipment. They will learn to use up-to-date crystallographic software
packages to solve and refine structures. Finally, they will present a
brief
report on their results.
The final five days of the course will be devoted to macromolecular
crystallography and include lectures on crystallization, data collection
and
processing, determination of heavy atom sites, structure solution by
MIR,
SIR, MAD, SAS and molecular replacement techniques, chain tracing, model
building and refinement methods.
In addition, experienced laboratory instructors will be available for
each
of the laboratory sessions. The text chosen for the summer school is
"Crystal Structure Analysis" by Glusker and Trueblood. A complete set of
lecture notes will be provided to each student.
For more information please see the web site at:
http://bcl15.bmb.uga.edu/aca01/index.html
or contact;
Dr. Gary Newton
Department of Biochemistry and Molecular Biology
University of Georgia
Athens, GA 30602
Telephone: (706) 542 - 3272
Fax: (706) 542 - 3077
E-mail: newton at chem.uga.edu
APPLICATION FORMS MUST BE RETURNED TO DR. NEWTON BY May 6, 2001
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2001 ACA Summer Course Outline and Schedule
Day 0 Thursday, June 7 Lobby - Georgia Center
Afternoon 2:00 - 10:00 PM Arrival and Registration
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DAY 1 Friday, June 8 Georgia Center
Morning
8:15 - 8:30 Welcome to Athens and Opening Remarks
8:30 - 9:30 Generation and Characteristics of X-rays
9:30 - 9:50 Refreshment Break
9:50 - 10:50 Preparation of Crystalline Samples
10:50 - 11:00 Break
11:00 - 12:00 Unit Cells, Lattices and Miller Indices
12:00 - 1:30 LUNCH (on your own)
Afternoon
1:30 - 5:00 Laboratory Sessions (locations to be announced)
Evening - Georgia Center
7:00 - 9:00 Mathematics of Crystallography
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DAY 2 Saturday, June 9 Georgia Center
Morning
8:30 - 9:30 Symmetry Elements
9:30 - 9:50 Refreshment Break
9:50 - 10:50 Space, Point and Laue Groups
10:50 - 11:00 Break
11:00 - 12:00 Use of International Tables for Crystallography
12:00 - 1:30 LUNCH (on your own)
Afternoon
1:30 - 5:00 Laboratory Sessions
Evening - Georgia Center
6:00 - 9:00 Opening Mixer - food and Drinks provided
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DAY 3 Sunday, June 10 Georgia Center
Morning
8:30 - 9:30 X-ray Diffraction and the Reciprocal Lattice
9:30 - 9:50 Refreshment Break
9:50 - 10:50 Symmetry in the Reciprocal Lattice
10:50 - 11:00 Break
11:00 - 12:00 Scattering by Single Atoms and Groups of Atoms
12:00 - 1:30 LUNCH (on your own)
Afternoon
1:30 - 5:00 Laboratory Sessions
Evening - Georgia Center
7:00 - 9:00 Q&A on previous three days of lectures
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DAY 4 Monday, June 11 Georgia Center
Morning
8:30 - 9:30 Structure Factors, Fourier Transforms etc
9:30 - 9:50 Refreshment Break
9:50 - 10:50 Anomalous Scattering
10:50 - 11:00 Break
11:00 - 12:00 Solving the Phase Problem
12:00 - 1:30 LUNCH (on your own)
Afternoon
1:30 - 5:00 Laboratory Sessions
Evening - Georgia Center
7:00 - 8:00 Instruments for Data Collection
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DAY 5 Tuesday, June 12 Georgia Center
Morning
8:30 - 9:30 Patterson Methods
9:30 - 9:50 Refreshment Break
9:50 - 10:50 Data Collection Methods/Cryocrystallography
10:50 - 11:00 Break
11:00 - 12:00 Processing Diffraction Data
12:00 - 1:30 LUNCH (on your own)
Afternoon
1:30 - 5:00 Laboratory Sessions
Evening - Georgia Center
7:00 - 8:00 Problem Structures
8:00 - 9:00 Crystal Twinning
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DAY 6 Wednesday, June 13 Georgia Center
Morning
8:30 - 9:30 Direct Methods I
9:30 - 9:50 Refreshment Break
9:50 - 10:50 Direct Methods II
10:50 - 11:00 Break
11:00 - 12:00 Structure Refinement by Least Squares
12:00 - 1:30 LUNCH (on your own)
Afternoon
1:30 - 5:00 Laboratory Sessions
Evening - Georgia Center
7:00 - 8:00 Historical Crystallography
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DAY 7 Thursday, June 14 Georgia Center
Morning
8:30 - 9:30 Structural Info & Error Analysis
9:30 - 9:50 Refreshment Break
9:50 - 10:50 Structure Report and Publication
10:50 - 11:00 Break
11:00 - 12:00 Structural Databases
12:00 - 1:30 LUNCH (on your own)
Afternoon
1:30 - 5:00 Georgia Center
***** STUDENT PRESENTATIONS *****
Evening- Georgia Center
7:00 - 9:00 BANQUET Georgia Center Banquet Area, room TBA
After Dinner
"History of the ACA Summer School"
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FRIDAY, JUNE 15 - Atlanta Sightseeing Trip!
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MACROMOLECULAR SESSIONS
DAY 8 Saturday, June 16 Georgia Center
Morning
8:30 - 9:30 Crystallization of Macromolecules
9:30 - 9:50 Refreshment Break
9:50 - 10:50 Introduction to HKL2000
10:50 - 11:00 Break
11:00 - 12:00 Introduction to XtalView
12:00 - 1:30 LUNCH (on your own)
Afternoon - Mini-Workshops (locations to be announced)
1:30 - 5:00 Group A XtalView Workshop
1:30 - 5:00 Group B HKL2000 Workshop
1:30 - 5:00 Group C Crystallization/Data Collection Workshop
Evening - Georgia Center
7:00 - 8:00 Crystallography on the International Space Station
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DAY 9 Sunday, June 17 Georgia Center
Morning
8:30 - 9:30 Synchrotron Data Collection
9:30 - 9:50 Refreshment Break
9:50 - 10:50 Overview of MIR/SIR/MAD/SAD
10:50 - 11:00 Break
11:00 - 12:00 Heavy Atom Derivatives & Location of HA Sites
12:00 - 1:30 LUNCH (on your own)
Afternoon - Mini-Workshops
1:30 - 5:00 Group B XtalView Workshop
1:30 - 5:00 Group C HKL2000 Workshop
1:30 - 5:00 Group A Crystallization/Data Collection Workshop
5:00 - 7:00 DINNER (on your own)
Evening - Georgia Center
7:00 - 8:00 Maximum Likelihood
8:00 - 9:00 Crystallography of the Nucleic Acids
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DAY 10 Monday, June 18 Georgia Center
Morning
8:30 - 9:30 MAD Theory
9:30 - 9:50 Refreshment Break
9:50 - 10:50 SAS Theory
10:50 - 11:00 Break
11:00 - 12:00 Introduction to the ISAS Procedure
12:00 - 1:30 LUNCH (on your own)
Afternoon - Mini-Workshops
1:30 - 5:00 Group C XtalView Workshop
1:30 - 5:00 Group A HKL2000 Workshop
1:30 - 5:00 Group B Crystallization/Data Collection Workshop
Evening - Georgia Center
7:00 - 8:00 Seminar - TBA
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DAY 11 Tuesday, June 19 Georgia Center
Morning
8:30 - 9:30 Molecular Replacement
9:30 - 9:40 Break
9:40 - 10:40 Model Building
10:40 - 11:00 Break
11:00 - 12:00 Stereochemistry and Structural Parameters
12:00 - 1:30 LUNCH (on your own)
Afternoon
1:30 - 3:30 Group A ISAS Workshop
3:40 - 5:40 Group B ISAS Workshop
Evening - Georgia Center
7:00 - 8:00 High-Throughput Crystallography
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DAY 12 Wednesday, June 20 Georgia Center
Morning
8:30 - 9:30 Refinement and Simulated Annealing
9:30 - 9:50 Refreshment Break
9:50 - 10:50 Structure Validation
10:50 - 11:00 Break
11:00 - 12:00 The Protein Data Bank
12:00 - 1:30 LUNCH (on your own)
Afternoon
1:30 - 3:30 Group C ISAS Workshop
4:00 - 6:00 Pizza Party
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