From sticher from bioc.unizh.ch Mon Aug 18 10:36:18 2008 From: sticher from bioc.unizh.ch (Patrick Sticher) Date: Mon Aug 18 10:36:33 2008 Subject: [Protein-crystallography] 6th NCCR Symposium on New Trends in Structural Biology: New Program / Registration deadline August 29 Message-ID: <48A996F2.2020508@bioc.unizh.ch> Dear colleagues, 6th International NCCR Symposium on New Trends in Structural Biology 8 + 9 September 2008, University of Z?rich, Z?rich, Switzerland NEW PROGRAM. The opening lecture will now be given by Gebhard Schertler about "Structure of the stress hormone receptor: beta1 adrenergic receptor". Confirmed plenary lecturers are Markus Gr?tter, Stephen C. Kowalczykowski, Kaspar Locher, Keiichi Namba, Poul Nissen, Andrej Sali, Gebhard F.X. Schertler, Jeffrey Skolnick, and A. Joshua Wand. The meeting will be held together with the Annual Meeting of the Swiss Society for Crystallography. Speakers of the society are Clemens Schulze-Briese and Colin Nave. Please see the symposium website for the complete program. REGISTRATION SLOT EXPIRES AUGUST 29. Please note that online registrations can be accepted for only a few more days until August 29. INFORMATION AND REGISTRATION. www.structuralbiology.uzh.ch/symposium2008.asp Please do not hesitate to contact me anytime if you need further information (sticher@bioc.uzh.ch). With best regards, Patrick Sticher The NCCR Structural Biology is a research initiative of the Swiss Science Foundation. Its research encompasses the fields of recombinant protein technologies, macromolecular structure determination and computational biomolecular sciences with a special focus on membrane proteins and supramolecular assemblies/interactions. 19 research groups from Swiss Universities and Research Institutions participate in this network. www.structuralbiology.uzh.ch/ _________________________________ Dr. Patrick Sticher Moser NCCR Scientific Officer Institute of Biochemistry University of Z?rich Winterthurerstrasse 190 CH - 8057 Z?rich Phone +41 / (0)44 / 635 54 84 Fax +41 / (0)44 / 635 59 08 From orry.molsoft from gmail.com Mon Aug 18 18:18:24 2008 From: orry.molsoft from gmail.com (Andrew Orry) Date: Wed Aug 20 08:30:14 2008 Subject: [Protein-crystallography] Protein Structure and Drug Design Workshop - MolSoft October 2-3 2008 Message-ID: <48AA0340.5060206@molsoft.com> MolSoft ICM Workshop: "Protein Structure and Drug Discovery" October 2nd to 3rd 2008 La Jolla, CA. Please see the following invitation to attend MolSoft's (www.molsoft.com) Protein Structure and Drug Design Workshop on October 2nd to 3rd 2008 in La Jolla, California USA. See www.molsoft.com/training.html for more information and a registration form. Our workshops are suitable for chemists and biologists who would like to learn more about computational drug discovery and bioinformatics. No prior knowledge in this field is required to participate. The workshop is presented by Prof. Ruben Abagyan (The Scripps Research Institute) and Dr. Maxim Totrov (MolSoft). The workshops will consist of lectures, demonstrations, and "hands-on" computational experiments and will cover the following topics: - Sequence and Protein Structure Analysis - Protein Modeling and Simulations - Structure Validation and Optimization - Ligand Binding Site Prediction - Small Molecule Docking and Virtual Ligand Screening - Structure-based development of target-specific compound libraries - Cheminformatics, chemical clustering, searching, superposition etc - QSAR, machine learning - Protein-Protein Docking We will demonstrate and train you in the use of many of our new developments in computational chemistry and biology including: - 3D Ligand Editor - design and optimize ligands interactively - Markush Library Docking - Multiple Receptor Docking (A method to incorporate receptor flexibility) - Automated model building into electron density - Atomic property field chemical superposition - Fast machine learning tools for QSAR - Pharmacophore drawing and searching - Compound library enumeration tools - Screen-grabbing movie making "The objective of this training workshop is to help chemists and biologists solve challenging problems in the area of drug discovery by efficient use of the science and technology present in ICM molecular modeling tools." Prof. Ruben Abagyan (The Scripps Research Institute and Co-Founder of Molsoft LLC) Please see our website at www.molsoft.com for more details or E mail andy@molsoft.com or call (858) 625 2000 ext.108. Please join the ICM Discussion Forum: http://groups.google.com/group/molsoft-icm-forum Latest Newsletter: http://www.molsoft.com/july08.html MolSoft is a La Jolla based company that is a primary source of new breakthrough technologies in computational chemistry and biology. Molsoft is committed to solving intellectually challenging problems in drug discovery and computational biology. -- Andrew Orry Ph.D. Senior Scientist MolSoft LLC 3366 North Torrey Pines Court Suite 300 La Jolla, CA 92037 U S A Phone: (858) 625-2000 (x108) Fax: (858) 625-2888 www.molsoft.com From acohen from slac.stanford.edu Wed Aug 27 18:32:10 2008 From: acohen from slac.stanford.edu (Cohen, Aina E.) Date: Sat Aug 30 15:19:01 2008 Subject: [Protein-crystallography] Pittsburgh Diffraction Conference - 2008 Message-ID: <274E6BE39062274CAF5C7153C839FD04017DBD79@exch-mail1.win.slac.stanford.edu> Dear Colleague: On behalf of the program committee, you and your colleagues are cordially invited to join us for the 66th Annual Pittsburgh Diffraction Conference to be held from October 30th - November 1st, 2008 in Pittsburgh, Pennsylvania at the Holiday Inn University Center. The goal of the conference is to bring together researchers in all areas of fundamental and applied diffraction and crystallographic research to present current topics. The program of the 2008 conference includes diffraction phasing, structure refinement and validation, synchrotron data collection, environmental science, materials science, chemistry and combined methods for structural biology research including NMR, Cryo-EM, EXAFS, and Raman spectroscopy. Conference speakers include: Sandy Asher, Department of Chemistry, University of Pittsburgh Pavel Afonine, The Berkeley Center for Structural Biology, LBNL Guillermo Calero, Department of Structural Biology, University of Pittsburgh Tom Caradoc-Davies, Protein Crystallography, Australian Synchrotron Paul Carey, Department of Biochemistry, Case Western Reserve University Yu-Sheng Chen, Microcrystallography, ChemMatCARS, APS James Conway, Department of Structural Biology, University of Pittsburgh Bryan Craven, Department of Chemistry, Indiana University of Pennsylvania Angela Gronendorn, Department of Structural Biology, University of Pittsburgh Bill Furey, Biocrystallography, VA Medical Center, University of Pittsburgh Roger Hendrix, Department of Biological Sciences, University of Pittsburgh Christian Jelsch, LCM3B, Nancy University, France Patrick Loria, Biophysical & Physical Chemistry, Yale University Jianpeng Ma, Biochemistry, Baylor College of Medicine Kanagalaghatta Rajashankar, NE-CAT, APS / Cornell University Kaustubh Sinha, Department of Biological Sciences, Carnegie Mellon University John Rose, Biochemistry & Molecular Biology, University of Georgia Nathaniel Rosi, Department of Chemistry, University of Pittsburgh Glenn Waychunas, Molecular Geochemistry & Nanoscience Group, LBNL Hui Wu, NIST Center for Neutron Research Junko Yano, Physical Biosciences, Lawrence Berkeley National Laboratory For more information about the conference program please visit the conference website: http://www.pittdifsoc.org/PDC_2008/schedule.htm . Poster sessions and social events, included in the program, provide many opportunities for formal and informal discussions with the speakers. The Chung Soo Yoo Award will be given to graduate students for best poster presentation. To insure maximum participation, the cost of attending the conference has been kept to a minimum. The conference will be preceded by a workshop for researchers intrigued by or new to crystallography titled, 'Crystallography Made Easy through Automation' on October 29th at the University of Pittsburgh, Structural Biology Department. This workshop will introduce what structural information crystallography can provide, the basics of crystallographic techniques (protein crystallization, x-ray diffraction data collection, and data analysis) and then demonstrate how these steps may be simplified by taking advantage of the automated facilities available at Stanford Synchrotron Radiation Laboratory and the Hauptman Woodward Medical Research Institute. The workshop is open to 24 participants and advanced registration is required. For more information and to register, please visit the workshop website: http://www-conf.slac.stanford.edu/crystallography . Discounted accommodations for the Pittsburgh Diffraction Conference and workshop attendees are available at the Holiday Inn University Center. The Holiday Inn is holding rooms at this discounted rate until October 8th. For additional information and instructions, please view our website at: http://www.pittdifsoc.org/PDC_2008/ or if you have any questions, please feel free to contact me directly. We look forward to seeing you in Pittsburgh ! Sincerely yours, Aina Cohen President-elect Pittsburgh Diffraction Society and Pittsburgh Diffraction Conference Session Organizers: Julian Adams, Paul Adams, James Conway, Steve Geib, Ana Gonzalez, Mark Macbeth, Apurva Mehta, Edward Snell, and Andy Vandenmark - - - - - - - - - - - - - - - - - - - - - Aina E. Cohen Staff Scientist Macromolecular Crystallography Group Stanford Synchrotron Radiation Laboratory SLAC / Building 120 / MS 99 2575 Sand Hill Road Stanford, CA 94025 P (650) 926-3125 F (650) 926-2258 - - - - - - - - - - - - - - - - - - - - -