synthetic lethality

[Marci Swede]

Excerpts from netnews.bionet.molbio.yeast: 5-Nov-93 Re: synthetic
lethality by Matthew Sachs at ADMIN.OGI. 
> These authors describe what might be called "synthetic vitality", a
> phenomenon  closely related to "synthetic lethality".  The paper describes
> the isolation of phage P22 conditional-lethal mutations that suppress
> missense lethal mutations in other genes.  "...Suppressor analysis ought to
> be especially useful for investigating proteins that engage in strong
> noncovalent interactions with one another."
> 
> Matthew Sachs



Actually, Jon Jarvik is faculty at Carnegie Mellon (where I'm a grad
student). He was teaching the course I referred to, and thus a
particularly funny remark, given his contributions to the field of
genetic interactions.

marci