carnitine biosynthesis mutant?

David R. Nelson dnelson at
Tue Apr 18 13:51:20 EST 1995

	  Due to redundancy in the function of the acyl-carnitine carrier and the
citrate carrier (both move acetyl-CoA out of the mitochondrial matrix) I am
seeking a strain with a defect in carnitine biosynthesis, to eliminate the
carnitine pathway for acetyl-CoA export from mitochondria.  Do any of you
have such a mutant you would be willing to share?  If not, do you know if
such a mutant exists?  Thanks.

David R. Nelson
Assistant Professor
Dept. of Biochemistry
University of Tennessee, Memphis

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