Signal Transduction Postdoc Avail/Boston

Thu Jan 12 14:45:06 EST 1995

Postdoctoral Position Available
Tufts University School of Medicine-NEMC
Boston, MA

We have an immediate opening for a  Postdoctoral Fellow to work in the 
field of molecular signaling 
and peptide-protein recognition.  The project focuses on the yeast mating 
peptide-receptor and the human thrombin 
receptor.  These receptors activate signal transduction pathways 
culminating in cell cycle mitotic arrest in 
the case of the yeast system and platelet aggregation in the case of the 
thrombin receptor.  Molecular 
biology techniques will be used to construct recombinant receptors 
and express these receptors in yeast 
strains.  Receptors will be characterized by various genetic and 
physical methods, purified, and labeled with 
affinity-peptides.  Insight into the molecular interactions between these 
peptides and their cognate receptors should provide leads for the 
development of anti-thrombotic agents.  The 
laboratory is located within the Center of Hemostasis and Thrombosis 
Research, a modern, state-of-the-art facility 
with a staff of 20 investigators including technical support.  Funds for 
this position derive from an NIH Training 
Grant in Hematology from the National Heart Lung and Blood Institute.  
Qualifications for this position are a 
Ph.D. degree and US citizenship or permanent residency.  Candidates with 
training in yeast genetics who would like 
to acquire expertise in protein chemistry are encouraged to apply.  
Interested candidates should send a 
letter describing their research interests, a CV, and names of 
three references to:

Athan Kuliopulos, MD., Ph.D. 
Departments of Medicine and Biochemistry 
Tufts-NEMC Box 832
750 Washington Street
Boston, MA 02111

617-636-4833 (fax)
akuliopu at

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