looking for RAS and Cyclin gene of yeast
BOCDC at CCVAX.SINICA.EDU.TW
BOCDC at CCVAX.SINICA.EDU.TW
Tue Jan 24 23:12:44 EST 1995
Hello and help:
I discoverd the expression of hepatitis B virus surface antigen in
yeast secretion pathway is able to induce abnormal growth of yeast S.
cerevisiae transformants(Current genetics, in press), high viability and redifferentiation(filamentous growth)
were found in starved culture, in my preliminary study, I found the
histone-H1 specific Kinase activity of p34(cdc28) is higher in the
abnormal yeast cell, It is difficult to understand the mechanism that how
the HBsAg triggers this abnormal growth, But I am trying to clarify this
phenomanan, So I looking for S. cerevisiae genes associated with p34 (
Cln1,2,3.. CLB1,2,...) or signal transduction pathway(Ras1, RAS2...),...
as probes to understand how the HBsAg interferes the host cell, if anyone
can provide any of these genes or any suggestions, please inform me :
Dz-Chi, Chen
Institute of Molecular Biology,
Academia Sinica, Nankang, Taipei,
Taiwan 115, ROC.
Fax: 886-2-782-6086
e-mail: in%"BOCDC at CCVAX.SINICA.EDU.TW"
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