Pombe postdoc/silencing, centromeres/ Scotland

[Phillip Lord]

	Medical Research Council
	Human Genetics Unit
	Edinburgh 
	Scotland UK

	EC Human Capital Mobility Post-Doc

	Up to 2 years funding available to work with 
	
	Dr Robin Allshire on:
	
	“"Silencing at the fission yeast centromeres as a means to 
	isolate components of the kinetochore complex"”
	
	The Successful applicant will further characterise mutants 
defective in centromere silencing and chromosome segregation. 
	Experience in molecular biology or yeast genetics and especially 
immunoprecipitation/protein purification would be an advantage.

	For background reading see:
Allshire RC et al (1994) Position effect variegation at the fission yeast 
centromeres Cell 76:157-170

Nimmo,R.E. et al (1994) Telomere associated chromosome breakage in 
fission yeast results in variegated expression of adjacent genes EMBO J 
13, 3801-3811

Allshire R.C et al (1995) Mutations derepressing silent centromeric 
domains in fission yeast disrupt chromosome segregation in fission yeast.
Genes and Development 9 218


	Applicants must be nationals of a community member state or 
associated state other than the UK and must not have carried out work in 
the UK for more than 2 years prior to the submission of an application.
	
	 
	In the first instance applicants should contact Dr Robin Allshire at 
MRC Human Genetics Unit, Western General Hospital, Crewe Road, 
Edinburgh EH4 2XU,SCOTLAND, UK.

	or  Tel (44)-31-343-2620 Fax: (44)-31-343-2620 or Email 
robin at hgu.mrc.ac.uk