Protein kinase C knockouts

Tomas Drgon tomasd at
Wed Nov 29 09:00:37 EST 1995

In article <49f52d$kq at>, bhalerao
<bhalerao at> wrote:

> Dear Netters,
> Could anybody out there provide me with information concerning PKC
>  genes cloned from S.cereviseae and S. pombe and the phenotypes of 
> mutants which have impaired PKC function.All the help will be greatly
> appreciated. Thank you
> Rishi

Hi. In cerevisiae a PKC1 deletion leads to lysis of cells with small buds.
The defect can be repaired by growing cells in 1 M sorbitol.
Names to look at: Yoshimi Takai, David Levin.

Tomas Drgon

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