okadaic acid sensitivity

LEIBOWITZ at OCELOT.RUTGERS.EDU LEIBOWITZ at OCELOT.RUTGERS.EDU
Tue Oct 1 22:24:52 EST 1996


Dear yeasters,

The phosphatase inhibitor okadaic acid inhibits some phosphatases extracted from
from yeast, as it does similar enzymes from "higher" organisms.  However, I 
have been unable to find any information on whether okadaic acid will act on 
the enzymes in intact  yeast cells, as it does in cultured vertebrate cells.  
I would be grateful to anyone who can provide info. about the in vivo effect 
of this compound on yeast.

Sincerely,
Mike Leibowitz
UMDNJ-RW Johnson Medical School



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