okadaic acid sensitivity

francis at NCBI.NLM.NIH.GOV francis at NCBI.NLM.NIH.GOV
Wed Oct 2 00:41:25 EST 1996


> From LEIBOWITZ at ocelot.rutgers.edu Wed Oct  2 01:06:32 1996

> The phosphatase inhibitor okadaic acid inhibits some phosphatases
> extracted from from yeast, as it does similar enzymes from "higher"
> organisms.  However, I have been unable to find any information on
> whether okadaic acid will act on the enzymes in intact  yeast cells, as
> it does in cultured vertebrate cells.  I would be grateful to anyone
> who can provide info. about the in vivo effect of this compound on
> yeast.
> 
> Sincerely,
> Mike Leibowitz
> UMDNJ-RW Johnson Medical School



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