Proline-rich activator domains in yeast.
vvsvetlov at utmem1.utmem.edu
Mon Sep 16 19:07:42 EST 1996
In article <bchemto-1309961032220001 at 18.104.22.168>,
bchemto at showme.missouri.edu (Juin Liu) wrote:
> Does anybody know if there are proline-rich activation domains
> functional in yeast (not only from yeast transcriptional activators,
> but from other organisms, too)?
P-rich domains are apparently active in yeast but more constrained by
requirement of proximity to the promoter than acidic activators (Kuntzler
et al., EMBO J., 1994, 13, 641-645). They are not common in yeast
activators but mammalian seem to be working with yeast transcriptional
machinery - to some extend at least. Another ref. for you - Kim & Roeder,
JBC, 1993, 268, 20866-20869 off the top of the ... stack of papers. Enjoy.
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