Final Announcement: Robotics Meeting

Andy Zaayenga andy.zaayenga at
Sun Jun 7 22:46:49 EST 1998

This is the final announcement for:

The Laboratory Robotics Interest Group 
June 1998 Meeting
The Fourth Annual Vendor's Night

Update: The meeting is this Thursday night. We invite you to join us for
this enjoyable evening. Sixty-four exhibitor tables will showcase the latest
in laboratory automation. Oral presentations on automation from the
viewpoint of users and manufacturers will be featured during the exhibition.
There will be hors d'oerves as well as pasta and beef tables, courtesy of
the exhibitors. Two cash bars will serve the attendees. There is never a fee
to attend our meetings. We look forward to seeing you!
Date: Thursday, June 11, 1998
Place: Forsgate Country Club, Forsgate Drive, Jamesburg, NJ 08831
       Phone: (732)521-0070
Itinerary: Exhibitions - 4:30 to 10:00 PM 
           Presentations - 7:00 to 9:30 PM
Member Pre-Registration: Requested, not required. Pre-registering will allow
us to more accurately gauge seating requirements and refreshment needs.
Indicate names of attendees and company affiliation. Pre-register by email
with <mailto:zaayenga at> or by phone at (732)302-1038. In
order to speed sign-in at the meeting, please bring a business card to drop
into the registration box. There will be a business card drawing for one of
our beautiful LRIG rosewood pens.
Agenda: Sixty-four vendor tables of laboratory automation hardware and
software will exhibit, demonstrating their latest products and services.
Presentations are featured in a separate hall during the exhibition. To be
considered for a presentation slot, please send us an abstract. Extensive
hors d’oerves, courtesy of the vendors, will be available as well as a cash
bar. The proceeds from this vendor funded exhibition are used to finance
mailings and pay for various costs of running the group. In this way the
LRIG can operate without collecting dues. Please support the group by
attending this informative and entertaining meeting. Last year’s Vendor’s
Night was extremely successful and we hope to surpass that turnout. For more
information contact Andy Zaayenga <zaayenga at>, Secretary, or
any of the LRIG officers listed below.
There are hotels nearby for attendees who wish to stay overnight. Members
interested in presenting a poster are encouraged to do so. Open career
positions at your company may be announced or posted. There is no fee to
attend the meeting.
Exhibiting Vendors:
Absorption Systems
Airfiltronix Corp.
Amersham Pharmacia Biotech
Argonaut Technologies
Beckman Instruments Inc.
Becton Dickinson Labware
Bohdan Automation Inc.
Brandel Biomedical
Cartesian Technologies, Inc.
Charybdis Technologies, Inc.
Comdisco Laboratory & Scientific Group
ComGenex USA Inc.
Corning, Inc.
CRS Robotics Corporation
Datavision Inc.
EG&G Wallac Inc.
EMAX Solution Partners
Fisher Scientific
Gensym Corporation
Gilson Inc.
Greiner America
Groton Neochem LLC
Hamilton Company
Hudson Control Group Inc.
InnovaSystems Inc.
Labman Automation Ltd
Labscientific Inc.
LEAP Technologies Inc.
LJL Biosystems
Marsh Biomedical Products
Matrix Technologies Corp.
MDL Information Systems
Molecular Devices Corporation
Nalge Nunc International
NEN Life Science Products Inc.
Packard Instruments
PerSeptive Biosystems
Robbins Scientific Corporation
Robocon Inc.
Skatron Instruments
Source For Automation Inc.
ST Robotics International
Tecan US Inc.
Titertek Instruments
Tomtec Inc.
Triad Scientific
Tropix Inc.
Universal Imaging Corporation
USA / Scientific Plastics
Vangard International Inc.
Waters Corporation
Xenopore Corporation
Zymark Corporation
Presentation:  Design strategy and implementation of an automated system for
performing Ultra High Throughput Screening using the current generation of
assay technologies

Mary Jo Wildey, Ph.D.
Research Fellow, New Leads Discovery, 
Robert Wood Johnson PRI, Raritan, NJ
Michael Girardi
Zymark Corporation

Expanding the new drug development pipeline is one of the keys to the race
to market for new drugs. Despite a number of promising new developments in
combinatorial chemistry and rational drug design most new leads still come
from empirical testing. This has placed an urgent emphasis on increasing the
throughput of screening to rates as high as 100,000 assays/day. While the
step to UHTS will offer several long term benefits, successful
implementation will depend on reducing the technical risks, maintaining
assay flexibility, and leveraging existing down stream and up stream

Some argue that the quantum step to 100,000 points per day will only be
realized with new assay technologies and emerging higher density plate
formats. This talk will discuss an automated approach which uses robust
production validated technology and allows current generation of assays to
be run at UHTS rates - today, with the flexibility to be easily reconfigured
to different assay formats, as needs change. Zymark has developed such a
solution called Allegroä , and is currently under contract with 4
collaborators. Some of the results of the first beta test with RW Johnson
Pharmaceutical Research Institute will be discussed. This includes methods
validation data on different assay formats, as well as preliminary
evaluation of the technology.
Presentation:  ORIGEN Technology for performing High-Throughput compound
screening assays

Charles Grimshaw, Ph.D.
IGEN Corporation

IGEN possesses a proprietary technology which utilizes
electrochemiluminescent detection to analyze levels of analytes, enzymatic
activities, binding events, nucleic acids, etc.. The technology delivers
highly sensitive and precise answers in a homogeneous format, allowing labs
to decrease the amount of rare reagents and labor required to discover hits
in target assays.
Presentation:  Industry Strategic Benefits and Success Factors in Automation
in Pharmaceutical Research

Michelle Palmer
Director, Assay Developmet Services
Mark T. Roskey, Ph.D.
Director, Pharmaceutical Screening Systems
Perkin-Elmer Tropix Inc.
Presentation:  Research Automation: An Integrated Approach to Proprietary
and Commercial Substance Supply, Preparation, Tracking, and Request
Fulfillment Using Novel Information Management Technology

David A. Kniaz
Project Director
EMAX Solution Partners

Companies that invest in leading combinatorial chemistry and high throughput
screening technologies need a way to manage the large volumes of proprietary
and commercial substance data created through these automated processes.
Research and development organizations can accelerate their drug discovery
process and control costs through an integrated substance management

This presentation will discuss how an integrated substance management
solution can bring the following basic elements of logistics management into

            *     reagent ordering and supply
            *     stockroom management
            *     container tracking
            *     proprietary compound inventory management
            *     micro-titer plate preparation and tracking
Presentation:  An Open, Modular Software Architecture for Laboratory
Carl Murray
Software Development Manager
Beckman / Sagian

Beckman Coulter's new operating environment for laboratory automation is a
robot-independent, application-independent architecture that allows
applications to be built from reusable, modular components. Each function,
such as device control, data logging, labware transportation, or execution
control, is managed by an independent module written industry-standard
programming tools. A messaging architecture allows these modules to work
together, and permits easy integration of any application that supports
ActiveX components, such as Microsoft Excel. Data management is
standardized, and data can be manipulated by several modules simultaneously.
New modules can be introduced without side effects, and old modules can be
updated without compromising the upgrade path of the system. An example of a
system built with this architecture, Beckman's Core Systems, is used to
illustrate the concepts.
Poster: Software methodology based on 3D molecular information

Siram N. V. Rao

Molecular Diversity Analysis based comparison of compound libraries.
3D-QSAR of millions of compounds.
HTS data analysis to identify false negatives and false positives.
Posters:  Automated Labelling and Weighing Systems

High Throughput Robotic Multistep Sample Preparation Procedure for the
Determination of Sodium Oxalate in Bauxite by Gas Chromatography

Wellplate Replication in High Throughput Screening

Andrew Whitwell
Labman Automation Ltd
For more information contact:

Executive Chair:
Dennis France 
dennis.france at
Novartis Pharmaceuticals Corporation

Andy Zaayenga 
andy.zaayenga at
TekCel LLC

Analytical Chemistry Chair and Treasurer:
William Haller 
bhaller at

High Throughput Screening Chair:
John Babiak, Ph.D. 
babiakj at
Wyeth-Ayerst Research

Agricultural Applications Chair:
Sharon Reed 
reeds at
American Cyanamid

Data Management Chair:
Steve Fillers, Ph.D. 
william.fillers at
Novartis Pharmaceuticals Corporation

>From the North or South: Take the New Jersey Turnpike to Exit 8A - Exit the
left ramp for Jamesburg (Route 32 East) - Continue straight for 1 1/4 miles
through traffic light - Forsgate Country Club is on your left - Use the
Clubhouse Entrance (second left).

>From Princeton: Route 1 to Scudders Mill Road East - Continue on Scudders
Mill Road and make a left at the 5th traffic light onto Dey Road - Continue
on Dey Road to the end  - Make a left  - At 2nd traffic light (Route 32)
make a right - Continue straight for 1 1/4 miles through traffic light -
Forsgate Country Club is on your left - Use the Clubhouse entrance (second
Group Update:  Paul Skerker of Leukosite and Donna Norton of Pharmalytic won
rosewood LRIG pen sets in the business card drawing.   A business card
drawing will be held at the June meeting.
Visit The Laboratory Robotics Interest Group homepage at

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