Yeast growth rate on galactose vs glucose
Peter haggie
p.m.haggie at bioc.cam.ac.uk
Tue Mar 17 11:03:32 EST 1998
Dear Yeast People
This retes to an old problem from 1996 that wasn't resolved as I could see.
Why do yeast grow more slowly on galactose than glucose?
Entry of gal is into glycolysis at the G-6-P stage
gal -> gal-1-P -> glu-1-P -> glu-6-P etc
This uses no more ATP than glucose entry (by my calculation) and so why does
gal mean that growth is so slow. Further, I ave been told that gal results
in cells that need to be respiring, ie thay do not produce ethanol. Any ideas.
I've tried lit searches, the Fraenkel revview and I am presently looking for
a new book called Carbohydrate metabolism with a chapter on yeast by Gancedo.
Any ideas?
Yours
Pete Haggie
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