Genes of related function close on genome?
gordonr at cc.UManitoba.CA
Mon Feb 22 08:34:04 EST 1999
I've predicted that in multicellular organisms this will be true of genes
involved in the same step of differentiation, at least for organisms
undergoing evolutionary radiation. See forthcoming book in my signature.
The "data" is in the form of conserved blocks within chromosomes across far
flung species. I've suggested we need to create GEMs, Gene Expression Maps,
in which each gene is labelled by the tissue in which it is first
expressed. Your question then becomes: do GEMs show clustering?
Yours, -Dick Gordon
>Are genes of related function clustered on the same chromosome and/or close
>together in sequence? Some say yes and some say no. What I would
>particularily like is a reference to a paper that has a statistical analysis
>of this question- anyone know of one?
Dr. Richard Gordon, Radiology, U. Manitoba, HSC, 820 Sherbrook Street,
Winnipeg R3A 1R9 Canada, Phone: 204-789-3828/The Hierarchical Genome &
Differentiation Waves: Novel Unification of Development, Genetics &
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