Disruption an essencial gene in diploid yeast

Kara Dolinski kara at genome.Stanford.EDU
Tue Apr 4 16:10:06 EST 2000

Hi Yiling, 

Your gene might be haploinsufficent. There's a few examples of this--I did
a search for haploinsufficiency and Saccharomyces at Medline.  Here's an
example of a reference describing a gene that exhibits haploinsufficency:


Best wishes,
 Kara Dolinski, Ph.D., Database Curator
 Saccharomyces Genome Database
 Stanford University Med. Ctr.
 Department of Genetics
 Stanford, CA 94305-5120 USA
 phone: (650)725-8956  fax: (650)723-7016
 e-mail:   yeast-curator at genome.stanford.edu
 WWW:   http://genome-www.stanford.edu/


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