Postdoc in Tilapia Genome Mapping

Thomas D. Kocher thomas.d.kocher at unh.edu
Tue Feb 27 12:20:36 EST 2001


POSITION AVAILABLE:   POSTDOCTORAL RESEARCH 
ASSOCIATE

COMPARATIVE PHYSICAL MAPPING OF THE TILAPIA GENOME

POSITION SUMMARY 
The goal of this USDA-funded project is to develop a comparative 
physical map of the tilapia genome to support positional cloning of 
genes controlling sexual differentiation, growth, color and body 
shape of this important aquaculture species.  The immediate task 
is to construct a database of fingerprints for 30,000 BAC clones by 
resolving fluorescently-labelled restriction fragments on a capillary 
sequencer.  The resulting contigs will be anchored to an existing 
genetic map of microsatellite polymorphisms by PCR screening of 
pooled BAC DNAs. We also aim to develop comparative gene 
maps with the forthcoming sequences of the pufferfish and 
zebrafish genomes.  

There is considerable scope for the postdoctoral associate to build 
a research program related to these comparative physical maps.  
Other work in the lab is directed at identifying genes underlying the 
rapid adaptive radiation of cichlid fishes in the lakes of East Africa.  

QUALIFICATIONS
Ph.D. with minimum 3 years experience in molecular biology.

APPLICATION PROCEDURE
Please send a cover letter describing your research interests, a 
complete CV and names of three references to:
                        Thomas D. Kocher, Professor
                        Dept. Zoology & Program in Genetics
                        216 Rudman Hall, University of New Hampshire
                        Durham, NH 03824
                        Tom.Kocher at unh.edu  http://tilapia.unh.edu

RECENT PUBLICATIONS FROM OUR LABORATORY

Kocher, T.D., W.-J. Lee, H. Sobolewska, D. Penman and B. 
McAndrew 1998.  A genetic linkage map of a cichlid fish, the tilapia 
(Oreochromis niloticus).  Genetics 148:1225-1232.  

Albertson, R.C., J.A. Markert, P.D. Danley and T.D. Kocher. 1999. 
Phylogeny of a rapidly evolving clade: the cichlid fishes of Lake 
Malawi, East Africa.  Proc. Natl. Acad. Sci. USA 96 (9): 5107-5110.

Streelman, J.T. and T.D. Kocher. 2000  From phenotype to 
genotype. Evolution and Development 2: 166-173.  

Carleton, K.L., F.I. H=E1rosi and T.D. Kocher.  2000 Visual pigments 
of African cichlid fishes : Evidence for ultraviolet vision from 
microspectrophotometry and DNA sequences.  Vision Research 
40:879-890.  

Albertson, R.C. and T.D. Kocher. 2001  Assessing morphological 
differences in an adaptive trait: a landmark-based morphometric 
approach to jaw morphology in Lake Malawi cichlid fish.  Journal of 
Experimental Zoology. (in press).

Danley, P.D. and T.D. Kocher. 2001.  Speciation in rapidly diverging
systems: lessons from Lake Malawi.  Molecular Ecology (in press).

UNH is committed to enhancing the diversity of its faculty and staff 
and encourages applications from women, persons of color, 
persons with disabilities and veterans.  

Thomas D. Kocher, Professor
Department of Zoology and Program in Genetics
University of New Hampshire
216 Rudman Hall
46 College Road
Durham, NH 03824
603-862-2115
FAX 862-3784
Tom.Kocher at unh.edu
http://tilapia.unh.edu








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