[Zbrafish] intron size
chi-bin.chien at neuro.utah.edu
Thu Jun 8 08:28:23 EST 2006
Having looked at the structure of quite a few axon guidance genes, I
can say that zebrafish intron size is much more like that of humans
than flies (as one would expect from the overall sizes of the three
genomes). Exon-intron structure is often highly conserved between
fish genes and their mammalian orthologs.
Of course, it would be best to take the mouse structure as a first
guess and then refine it by looking at actual fish cDNA and gDNA
At 10:46 AM -0700 6/7/06, kovalick_g at utpb.edu wrote:
>Does anyone have information as to the average size of zebrafish
>introns? Do they tend to be as large as mammalian introns, or smaller
>like Drosophila introns, or somewhere in-between? Does intron position
>tend to be conserved between zebrafish and mammalian genes? Can I use
>intron size and position in a mouse gene as a reliable guide to intron
>size and position in the homologous zebrafish gene?
>I'd be grateful for any information on this topic.
>Department of Science and Mathematics
>University of Texas of the Permian Basin
>Odessa, TX 79762
>Zbrafish mailing list
>Zbrafish at net.bio.net
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