[Zbrafish] Group Leader Opportunities at the Center for Regenerative Therapies Dresden

Christian Boekel boekel at mpi-cbg.de
Thu Jun 15 09:47:37 EST 2006

The new DFG Research Center Regenerative Therapies Dresden (www.crt- 
dresden.de) focuses on fundamental research into Regeneration, Tissue  
Engineering and Stem Cells. In a joint effort of several scientific  
institutions in Dresden, it forms a network of currently 54 research  
groups plus commercial partners, working in the areas of Haematology/ 
Oncology, Diabetes, Neurodegenerative disorders, Bone/Cartilage  
replacement and Cardiovascular disease. Available immediately, we  
offer positions of limited duration for

8 Junior Research Group Leaders.

The period of employment is in accordance with the Framework Act of  
Higher Education (Hochschulrahmengesetz – HRG) as amended.  
Remuneration is offered in accordance with the salary scale BAT-O Ia;  
individual salaries depend on the candidates' personal and  
educational background and work experience. Applicants are expected  
to have an outstanding international scientific qualification in  
biomedical research.

The Junior Research Groups will run for 6 years. They are subject to  
a time limit which is

31 December 2009. Prior to the expiration of the contract, an  
evaluation is conducted to assess further extension of the contract  
and the conversion of 3 of the 8 Group Leader positions into  
permanent W2 professorships (tenure track option). Each group  
consists of the position for the group leader, one postdoc, one PhD  
student and one technical assistant. The basic equipment and running  
costs are available. Together with 3 additional new professorships,  
the new junior research groups will be housed in a new state-of-the- 
art building equipped with a shared central technology platform. The  
new building will be located next to the BIOTECnology Center of the  
TUD (www.biotec.tu-dresden.de) and the Max-Planck Institute of  
Molecular Cell Biology and Genetics (www.mpi-cbg.de) on the Medical  
School Campus. Key avenues for research efforts in the new center  
will complement the existing strengths.

The Research Center is particularly interested to appoint group  
leaders working in the following areas:

•      Animal models of regeneration (J1). The goal is to understand  
regeneration in relation to progenitor cell development in vertebrate  
model organisms and tissues that have, as a natural phenomenon,  
excellent abilities to regenerate, e.g. amphibians or zebrafish.

•      Preclinical approaches of stem cells in regenerative therapy  
(J2). The goal is to perform translational research for specific stem  
cell types that are approaching use for human clinical therapy, e.g.  
mesenchymal stem cells and neural stem cells.

•      Cell biological basis of stem cell/progenitor cell development  
(J3, J4). Recognizing the overwhelming need for better understanding  
of cell biological mechanisms in stem cell activity for all research  
areas, these research teams will specifically investigate critical  
mechanisms controlling stem cell activity.

•      Engineering of stem cell behavior using materials science  
approaches (J5, J6). The goal is to understand and engineer scaffolds  
and matrices mimicking the extracellular environment that either  
support or prevent regeneration/stem cells, and to model this  
environment in suitable in vivo assays.

•      Nanotechnological control/engineering of tissue regeneration  
(J7). The goal will be to achieve specific engineering and  
nanotechnological designs of e.g. functionalized surfaces,  
microvalves and controllable hydrogels that allow a spatial and  
temporal specific stimulation of stem cell populations.

•      Immunotolerance in regeneration (J8). Host immune reactions  
are a serious problem in type I diabetes and transplantation of  
organs, stem cells or engineered tissues alike. Using animal models,  
the group will research immunological and genetic means of inducing  
immunotolerance, e.g. by selective epitope or reactive lymphocyte  

Please indicate which position(s) you are applying for.

For further information, see www.crt-dresden.de and www.biotec.tu- 
dresden.de. Women are specifically encouraged to apply. Handicapped  
applicants are favored given otherwise identical qualification.  
Applications and two letters of recommendation should be sent by July  
28th, 2006  to the following address: TU Dresden, BIOTEC, Prof. Dr.  
Michael Brand, Speaker of the CRTD, Tatzberg 47-51, 01307 Dresden,  
Germany; email: director at biotec.tu-dresden.de.


Dr. Christian Boekel
BIOTEC, TU Dresden
Tatzberg 47-51
01307 Dresden
(+49) 351-46340032

christian.boekel at biotec.tu-dresden.de

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