[Zbrafish] Ph.D. scholarship in Host-Virus interactions (in fish)

bdschyth via zbrafish%40net.bio.net (by bdschyth from gmail.com)
Fri Jun 25 13:15:19 EST 2010

A 3 year PhD position studying host-virus interactions in rainbow
trout is available at the National Veterinary Institute, Technical
University of Denmark (DTU). The place of work is Aarhus, Division of
Poultry, Fish and Fur Animals. The candidate will be linked to the
Research Group for Fish Immunology and Vaccinology.

The PhD project is an integrated part of a larger National Research
project with focus on co-evolutionary aspects of host and virus on
both genetic and phenotypic levels. The project will include shorter
stays at research institutes outside of Denmark.

Job description
The overall scientific aim of this PhD project is to disclose and
characterise the mechanisms involved in immunity to a lethal fish
rhabdovirus (viral haemorrhagic septicaemia virus, VHSV). A DNA-based
vaccine inducing a highly protective immune response here represents
an important tool along with immuno assays and molecular biology
techniques. A major task will be to determine mRNA and miRNA response
profiles to vaccination and/or infection and to correlate these with
the phenotypic traits (level of immunity, humoral and cellular immune
response). Gene expression analysis will be an important activity, but
work at all levels including also functional studies of virus
propagation in cell culture as well as wet lab vaccination and
infection trials should be expected. Publishing of results in
scientific journals will represent an integrated element. A number of
training courses will be included in the PhD study.

Applicants should meet the following qualifications:
A master's degree in either veterinary medicine, biology or a
comparable discipline or a similar degree with an academic level
equivalent to the master's degree
Experience in immunology, virology and/or molecular biology research
An interest in scientific understanding of host-pathogen interactions,
aiming at development of strategies for disease prophylaxis
Fluency in English speaking and writing
Good skills in scientific communication and innovative thinking, good
social skills

Approval and Enrolment
The scholarships for the PhD degree are subject to academic approval
and the candidates will be enrolled in one of the general degree
programmes of DTU. For information about the general requirements for
enrolment and the general planning of the scholarship studies, please
see the DTU PhD Guide.

Salary and appointment terms
The salary and appointment terms are consistent with the current rules
for PhD degree students. The period of employment is 3 years.

Further information
For further information please contact Senior Scientist Niels
Lorenzen, 3588 6829.

You can read more about National Veterinary Institute at www.vet.dtu.dk

Deadline for application is 15 August 2010. Please open the link
"apply for this job online" at:
, fill in the application form and attach:

A motivation describing why you are interested in this position
A CV including publications
Copy of certificate with grades
All interested candidates irrespective of age, gender, race, religion
or ethnic background are encouraged to apply.

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