I would like your help in identifying a commercially available metaloproteinase inhibitor.
I have a series of experiments that I want to run in which I need to prevent a
cell surface protein from being cleaved from the surface of a cell by a
metaloproteinase. Specifically, I want to prevent membrane bound TNF from
being cleaved and appearing in the supernatant. Does anyone have experience
with a small molecule inhibitor that I could use?
Thanks
George A. Heavner
Senior Director, Peptide R&D
Centocor, Inc.
