Advanced Linkage Course Jurg Ott
October 19-23, 1992 University of Zurich, Switzerland (Ir-
chel Campus Computer Center, 12 IBM
PS/2's), Proff. Eric Kubli (Zurich) and
Jurg Ott (New York).
Maximum number of participants is 12.
Application deadline: August 25, 1992.
TOPICS include: Theory of linkage programs. Practical exercises
using the LINKAGE and other programs. Handling of inbreeding
loops, age-dependent penetrance, and sex-specific recombination
fractions. Problems of interference in multipoint mapping.
Models of genetic heterogeneity. Calculation of genetic risks,
also under allelic and nonallelic association. Linkage analysis
with quantitative trait loci, biological covariates, and pseudo-
autosomal loci. Computer simulation methods. Gene mapping in
CEPH reference families.
Participants must be familiar with IBM PCs or compatible micro-
computers. Extensive experience with a linkage program and/or a
good background in statistical genetics and linkage analysis are
additional criteria for admission.
To obtain further information and an application form, contact:
Katherine Montague, Course coordinator, Columbia University Unit 58
722 West 168th Street, New York, NY 10032
Tel +1-212-960-2507 Fax +1-212-568-2750 E-mail: OTT at NYSPI.BITNET