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ANNOUNCEMENT: Release 2 of TREMBL, a protein sequence database supplementing SWISS-PROT

Rolf Apweiler apweiler at uranus.ebi.ac.uk
Mon Feb 24 04:00:15 EST 1997


INTRODUCTION
============

TREMBL is a protein sequence database supplementing the SWISS-PROT Protein
Sequence Data Bank. TREMBL contains the translations of all coding 
sequences (CDS) present in the EMBL Nucleotide Sequence Database not yet
integrated in SWISS-PROT. TREMBL can be considered as a preliminary 
section of SWISS-PROT. For all TREMBL entries which should finally be 
upgraded to the standard SWISS-PROT quality, SWISS-PROT accession numbers 
have been assigned.


RELEASE 2.0 OF TREMBL
=====================

This TREMBL release is created from the EMBL Nucleotide Sequence Database
release 49 and contains 116'379 sequence entries, comprising 31'293'053 
amino acids. 


TREMBL is split in two main sections; SP-TREMBL and REM-TREMBL:

SP-TREMBL (SWISS-PROT TREMBL) contains the entries (96'757) which should be 
eventually incorporated into SWISS-PROT. SWISS-PROT accession numbers have 
been assigned for all SP-TREMBL entries. 

SP-TREMBL is organized in subsections:

fun.dat (Fungi):                3108 entries
hum.dat (Human):                4541 entries
inv.dat (Invertebrates):       13269 entries
mam.dat (Other Mammals):        1740 entries
mhc.dat (MHC proteins):         2307 entries
org.dat (Organelles):           6705 entries
phg.dat (Bacteriophages):        884 entries
pln.dat (Plants):               5699 entries
pro.dat (Prokaryotes):         23331 entries
rod.dat (Rodents):              4769 entries
vrl.dat (Viruses):             28150 entries
vrt.dat (Other Vertebrates):    2254 entries


REM-TREMBL (REMaining TREMBL) contains the entries (19'622) that we do 
not want to include in SWISS-PROT. 


WEEKLY UPDATES OF TREMBL
========================
Weekly cumulative updates of TREMBL will be available by anonymous FTP and 
from the EBI SRS server from the beginning of March 1997 onwards.


ACCESS/DATA DISTRIBUTION
========================

FTP server:     ftp.ebi.ac.uk/pub/databases/trembl
SRS server:     http://www.ebi.ac.uk/srs/srsc

TREMBL is also available on the SWISS-PROT CD-ROM.
SP-TREMBL is searchable on the FASTA server of the EBI and will be soon 
searchable on the BLITZ server of the EBI.



TREMBL HAS BEEN PREPARED BY:
============================

Rolf Apweiler, Sergio Contrino, Vivien Junker, Stephanie Kappus, 
Fiona Lang, Michele Magrane, Maria Jesus Martin, Nicoletta Mitaritonna 
and Claire O'Donovan at the EMBL Outstation - European Bioinformatics 
Institute (EBI) in Hinxton, UK;
Amos Bairoch and Alain Gateau at the Medical Biochemistry Department of 
the University of Geneva, Switzerland.


=======================================================================
Rolf Apweiler                           | SWISS-PROT Coordinator
EMBL Outstation                         | Email:apweiler at ebi.ac.uk
European Bioinformatics Institute (EBI) | URL:  http://www.ebi.ac.uk
Wellcome Trust Genome Campus, Hinxton   | Tel:  +44 (1223) 494435
Cambridge CB10 1SD, UK                  | Fax:  +44 (1223) 494968
========================================================================








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