To the best of my knowledge intense research along these lines was conducted at
a couple of companies using GFP in various forms. In fact, it is likely that some
of these phosphate dependent fluorescent peptide have been constructed and
successfully tested already.
Eugene.
A. S. Goustin Lab wrote:
> Wouldn't it be useful to dissect signal transduction pathways to have a
> peptide substrate (or peptide substrate mimetic) which would emit an
> altered fluorescence (band-shifted) depending on its state of
> phosphorylation?
>