Applications are invited for a POST-DOCTORAL POSITION in the group of Tom
Misteli at the National Cancer Institute, NIH, Bethesda, MD. The
laboratory studies the molecular mechanisms which control nuclear
architecture and function in-vivo, particularly the coordination of
transcription and pre-mRNA splicing (see Nature, 1997, 387, p.523,
Science, 1997, 276, p.1495, Curr. Opi. Cell Biology, 1998, 10, p. 323). In
addition, we are analyzing the spatial organization of genes and
chromosomes within the interphase cell nucleus. We use conventional and
time-lapse fluorescence microscopy of living cells in conjunction with
molecular methods to address these cell biological aspects of gene
expression. The laboratory is closely associated with a new NCI imaging
facility equipped for laser scanning confocal microscopy, deconvolution
methods, in-vivo microscopy, 4D-image analysis and multi-color cytogenetics.
Candidates must have experience in fluorescence microscopy and molecular
biology techniques. Knowledge of cytogenetic techniques (FISH, chromosome
painting etc.) is an advantage.
The NCI provides outstanding resources and a large, interactive environment
to perform high level innovative research. The successful applicant will
have the opportunity to develop his/her own projects within a highly
interactive team.
This NIH funded position is available from January 1999. Please send CV
including a list of publications and names of three referees to Tom
Misteli, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724 USA,
email: misteli at cshl.org
Cold Spring Harbor Laboratory
Cold Spring Harbor, NY 11724
T: 516 367-8478
F: 516 367-8876
misteli at cshl.org
