In article <1992Aug6.075459.16300 at gserv1.dl.ac.uk>, MBFBPED at UK.AC.MCC.CMS (andy
brass) says:
>>I was wondering if anyone on this group knew of any theoretical work
>which might have been done to understand the phenomena of Th subset
>polarisation - particular in regard to understanding how the cytokine
>interactions between the Th subset cells might control the process
>(to help interpret in vivo depletion experiments). I am aware that a
>lot of work has been done on developing theoretical models to explain
>the behaviour of the humoral immune system - has anything similar been
>attempted for cellular immunity?
To help those of us who might want to reply to your questions perhaps you
would supply the following information.
(i) How many T cell subsets do you recognize?
(ii) What is T cell subset "polarization"?
(iii) How are you carrying out your "in vivo depletion" experiments?
Sincerely, Don Forsdyke