I was wondering if anyone on this group knew of any theoretical work
which might have been done to understand the phenomena of Th subset
polarisation - particular in regard to understanding how the cytokine
interactions between the Th subset cells might control the process
(to help interpret in vivo depletion experiments). I am aware that a
lot of work has been done on developing theoretical models to explain
the behaviour of the humoral immune system - has anything similar been
attempted for cellular immunity?
Andy Brass - University of Manchester
