Hello fellow netters,
Here is a question that maybe a real immunologist can answer.
The majority of T-cells express the alpha/beta heterodimer on their
surface. A smaller number of cells express however the beta/gamma
combination. This seems mutually exclusive. My question is the
following: are all of these genes rearranged, regardless which
ones are expressed? Or are only the gamma and delta rearranged in
the g/d expressing cells and are only the alpha/beta rearranged in
the a/b expressing cells.
Is this known? Does anyone know, and have a reference to this?
Thanks in advance.
Johan de Boer
jdboer at sol.uvic.ca
