IUBio

familial granulomatosis

RAPHAEL at VM.TEMPLE.EDU RAPHAEL at VM.TEMPLE.EDU
Wed Dec 29 19:57:52 EST 1993


Organization: Temple University
Keywords: granuloma
X-Newsreader: NNR/VM S_1.3.2

I am investigating the syndrome of familial granulomatous arthritis, uveitis
and rash.  This is the only known example, in humans, of a multisystem,
granulomatous inflammatory condition inherited in an autosomal dominant manner.
I would like to hear from anyone who may care/investigate such patients and/or
has an interest in the basic immunology of granuloma formation.  My research
group is in the midst of a linkage analysis to try and isolate the putative
gene chromosomal location and a study to better define the immunobiology of
the condition.



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