For the assistance of new subscribers, I enclose a list of possible topics from
our original "charter".
Topics of interest would be:
Mechanism of self/not-self discrimination
Evolution and role of MHC polymorphism
Two signal hypotheses
Education of T cells
Education of B cells
T cell and B cell cooperation
G0/G1 switch to activate ICCs (immunologically competent cells)
Mechanisms of ICC deletion or suppression
T cell receptors
B cell receptors
Lymphokines
Signal transduction pathways
Complement
Parasite strategies to avoid the immune response
Why does not a placental mammal not reject the fetal "graft"
Relationship of heat-shock response to intracellular self discrimination
Mechanism of action of cyclosporine
The acute phase response
Role of fever in infections- positive or negative?
Etc.
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Sincerely,
Don Forsdyke, Discussion Leader
