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Lymphocyte transformation (EBV, anti-CD3...)

Milan Jira ULIMJ at CSPUNI12.EARN
Thu Jan 7 06:51:53 EST 1993


Subject:      Re: Lymphocyte transformation by EBV - help wanted
 
    I also believe that the lymphocyte transformation induced by anti-CD3
antibody has (if long acting..) temporarly effect on EBV-induced transformation
The procedure of T cell depletion certainly increase the level of EBV induced
transformation, as described.
 
The receptor on B cells for EBV is type II complement receptor (CD21). Does
anybody know if anti-CD21 has specific stimulatory effect of B cells?
 
Milan Jira, M.D., Ph.D.
Dept. of Immunology
3rd Medical Faculty, Charles University
Prague, Czech Republic



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