GORDON CONFERENCE ANNOUNCEMENT
Some places are available for the GORDON RESEARCH CONFERENCE on
NEUROIMMUNOLOGY, to be held this coming June 13-18, at Colby-Sawyer College
in New Hampshire. Financial assistance is available for applicants who may
need it. Contact Dr. Lois Lampson (lampson at cnd.bwh.harvard.edu; phone
617-732-7015; FAX 617-732-7787) or the Gordon Conference organization
(BCP101 at URIACC; phone 401-783-4011; FAX 401-783-7644). Program:
GORDON RESEARCH CONFERENCES
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BIOLOGY OF THE IMMUNE RESPONSE TO ANTIGEN WITHIN THE CNS
June 14-18, 1993
Colby-Sawyer College, New Hampshire
Lois A. Lampson, Chair
Monday a.m.: REGULATION OF THE MAJOR HISTOCOMPATIBILITY COMPLEX WITHIN THE CNS
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W. Armstrong: "Current MHC overview: Distribution, regulation, MHC-antigen
complexing."
K. Ozato: "Molecular biology of MHC class I regulation: Special CNS
mechanisms?"
J. Ting: "MHC class II regulation: Special CNS mechanisms?"
E. Cowan: "When is MHC up-regulation seen in the CNS? What functions are
served?"
Monday p.m.: PHARMACOLOGIC CONTROL OF THE IMMUNE RESPONSE TO ANTIGEN WITHIN THE
CNS
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B. Arnason: "The universe of regulatory molecules: Effects of
"neurotransmitters" on lymphocytes; of "lymphokines"
on neural cells."
E. Frohman: "Immuno-regulatory molecules produced within the CNS itself."
F. Lublin: "Regulation in vivo: Cytokine with opposing effects on
different cells."
Tuesday a.m.: CONTROL OF LEUKOCYTE ENTRY AND MIGRATION WITHIN THE BRAIN
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R. Melder: "The biophysics of leukocyte circulation: How much can it
explain?"
D. Male: "Signals and adhesion molecules at the cell/brain interface:
Unique to brain?"
A. Vortmeyer "Independent control of leukocyte entry and migration through
the brain."
Tuesday p.m.: IMMUNE EFFECTOR MECHANISMS THAT ARE ACTIVE IN THE CNS
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J. Sedgwick: "Antigen presentation and MHC-restricted T cell functions within
the CNS."
J. Antel: "The range of cell-mediated effector functions: Are any unique
to the CNS?"
W. Hickey: "Other" cells in the CNS: When do they enter and leave? What
do they do?"
Wednesday a.m.: HOW CNS TUMOR AND VIRUSES REGULATE THEIR IMMUNE ENVIRONMENT
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M. Kuppner: "How brain tumors affect their immune environment".
L. Mucke: "How viruses change their immune environment."
C. Petito: "AIDS-associated changes that can facilitate opportunistic CNS
infection."
Wednesday p.m.: BENEFICIAL IMMUNE RESPONSES AGAINST TUMOR AND VIRUS WIHTIN THE
CNS
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L. Lampson: "Anatomy of CNS immuno-regulation: Importance of site within
the brain, site within the tumor, site of antigen within the
cell."
P. Doherty: "Effector mechanisms and target cells in CNS viral infections."
Thursday a.m.: DELETERIOUS IMMUNE RESPONSES TO ANTIGEN WITHIN THE CNS
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M.K. Nicholas: "Effector mechanisms in CNS graft rejection: Unique to the CNS?"
R. Sobel: "Effector mechanisms in CNS autoimmunity: Unique to the CNS?"
J. Posner: "Paraneoplastic syndromes: Potential effector mechanisms."
R. Hohlfeld: "Muscle immunobiology: How does it compare to that of the CNS?"
Thursday p.m.: EQUIVOCAL AND SECONDARY IMMUNE RESPONSES IN THE CNS
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P. McGeer: "MHC upregulation and other signs of immune activation in
"nonimmunologic" disorders: What do they imply?"
Friday a.m.: SYNTHESIS: GENERAL DISCUSSION AND REMARKS BY SELECTED
PARTICIPANTS
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What is unique about the immune response to antigen within the CNS?
Beneficial and deleterious CNS immune responses: Two sides of
the same coin.
_____________________________________________________________________________
Poster sessions. Please submit a brief poster abstract (<250 words) with
application. Some abstracts may be selected for oral presentation.
Obtain application from:
Gordon Research Conferences/Neuroimmunology Conference
Gordon Research Center
University of Rhode Island
Kingston RI 02881-0801
Phone (401)783-4011; FAX (401)783-7644
or from:
Dr. Lois Lampson, Dept. of Neurology
LMRC 116, Brigham and Women's Hospital,
Boston MA 02115
Phone (617)732-7015; FAX (617)732-7787.
