In article <ibelgaufts-091193162809 at lmubmac26.biochem.mpg.de>, ibelgaufts at vms.biochem.mpg.de (horst ibelgaufts) writes:
>Dear netters, does anyone out there know anything about the species
>specificity of human stem cell factor? Does it work on murine bone marrow
>(stem) cells?
>Thanks
>Horst Ibelgaufts
>Institute of Biochemistry, MPI of Biochemistry
>Munich Martinsried, FRG
>ULTRA POSSE NEMO OBLIGATUR
While I don't have a specific answer to your question, the following
reference has been offered:
F.H. Martin; "Cell"; volume 63; pgs. 203-211; (1990)
the paraphrased title being "Structural & functional expression of rat &
human SCF DNA."
As stated above, we do not know definitively, but indications are that it
very well may work in murine systems. If you check there was evidently a
flurry of articles around the same time.
If you are interested in an iodinated SCF (I-125), please get in touch with
me for further details. (refer to catalog # NEX-283). This one is human,
recombinant.
I hope this is of some help.
Best Regards,
Charly Ott DuPont-NEN Research Products - Technical Support
E-MAIL = OTTCR at ESVAX.DNET.DUPONT.COM
PHONE = 800-772-2636