Hi, immuno-netters,
Does anyone know when/where complement-like proteins appeared in
phylogeny? I just ran a MEDLINE search back to 1980, and received
abstracts of several interesting articles. However, they apparently
have considered only vertebrates. What about complement homologs (or
analogs) in invertebrates? It seems to me that both lysis (of enemies)
and chemotaxis, activation of phagocytosis, activation of intracellular
lytic processes, etc., would all be useful to unicellular
organisms as well as to mammals. Obviously, vasoactive mediators are
only useful if you have a vasculature.
Reply either to this newsgroup or by e-mail.
Thanks, Jerry
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+ Gerald L. Bartlett, M.D., Ph.D. Phone: 309-671-8440 +
+ Professor and Chairman of Pathology FAX: 309-671-8513 +
+ University of Illinois College of Medicine @ Peoria +
+ Box 1649, Peoria, IL 61656-1649 e-mail: u56149 at uicvm.cc.uic.edu +
+ 1 Illini Drive, Peoria, IL 61605-2576 u56149 at uicvm.bitnet d +
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