Dear Netters,
We are organising a Group Discussion on Programmed Cell Death, here in
the Tata Instt. of Fundamental Research in Bombay ; India. Since nobody here
actually works on Apoptosis of any kind, our preparatory to the G.D has
put us up against quite a few double-edged questions (.. unanswered, atleast
in the papers that we have seen..) which we hope some of you may be able
to help us out with !
One question that we have been arguing quite a lot about is the definition
of Programmed Cell death itself ! Is there any solid reason to believe that
there is any OTHER kind of "normal" cell death (excluding necrosis) ?
Another aspect we'd like clarification about is the manner of disposal of
apoptic bodies after engulfment. Are they degraded via the normal phagosomal
pathway ? Or is there some sort of a "re-cycling" of the organelles, without
actual degradation ?
Though we understand that that it is a debatable issue, I would also like
your opinions on whether phagocytosis of these apoptic bodies are receptor
mediated & how lipid assymetry may actually help in the process.
P.S. The G.D here, is on 23-April. Any suggestions to make it an
exciting session are welcome, too !
Thanking you,
Nevil J.S
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| Molecular Biology Unit, * Ph. 215 29 71 |
| Tata Instt. of Fundamental Research, * Ext. 2570 |
| Homi Bhabha Road, * Fax 091-22-2152110 |
| Colaba, BOMBAY-400 005 * |
| India. * E-m nevil at TIFRVAX.TIFR.RES.IN |
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