Does anyone know anything about the relative binding of B7-1 and B7-2 to
CD28 vs CTLA-4? Or is the fact that we have two ligands for two receptors,
one of each pair being induced after activation, mere coincidence?
On a more pedantic note, does anyone worry that there is already a murine
cell surface marker B7(2), related (I think) to HSA?
Cheers,
Paul
--
Paul J Travers phone : +44-(0)71-631-6262 (office)
ICRF Structural Biology Unit " " " 6268 (lab)
Birkbeck College fax : +44-(0)71-436-8918
Malet Street
London WC1E 7HX email : p_travers at icrf.icnet.uk
England or : paul at histo.cryst.bbk.ac.uk