IUBio

Charter of Bionet.immunology

FORSDYKE at QUCDN.QueensU.CA FORSDYKE at QUCDN.QueensU.CA
Tue Jan 18 16:07:48 EST 1994


There has been some talk recently about the purpose of Bionet.immunology.
Here, in case you missed it, is our original "charter".
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Discussion leader:      Donald R. Forsdyke
                        Department of Biochemistry,
                        Queen's University,
                        Kingston, Ontario, Canada K7L3N6


Topics of interest would be:

   Mechanism of self/not-self discrimination
   Evolution and role of MHC polymorphism
   Two signal hypotheses
   Education of T cells
   Education of B cells
   T cell and B cell cooperation
   G0/G1 switch to activate ICCs (immunologically competent cells)
   Mechanisms of ICC deletion or suppression
   T cell receptors
   B cell receptors
   Lymphokines
   Signal transduction pathways
   Complement
   Parasite strategies to avoid the immune response
   Why does not a placental mammal not reject the fetal "graft"
   Relationship of heat-shock response to intracellular self discrimination
   Mechanism of action of cyclosporine
   The acute phase response
   Role of fever in infections- positive or negative?
   Etc.

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