In article <3atgkc$d5j at agate.berkeley.edu>, frauwirt at notmendel.Berkeley.EDU (Ken
Frauwirth (BioKen)) says:
>>This argument assumes that the specific epitopes found on the ICC's are at
>frequencies high enough to be detected. If a given epitope is found only on
>a single cell, it is unlikely that it will be able to "educate" future ICC's.
If, once it has survived the education process, the ICC goes on to
release "natural antibody", then there should be sufficient epitopes. B cells
probably release natural antibody. But do T cells shed receptors? I suspect not
so your point would seem more pertinent with respect to T cells.
Sincerely, Don Forsdyke
