DPIGG writes:
> From BIOSCI-REQUEST at net.bio.net Tue Nov 29 19:20:18 1994
> To: immunology at net.bio.net> From: dpigg at aol.com (DPIGG)
> Subject: Antibody production without B cells.
> Date: 29 Nov 1994 19:31:51 -0500
> Sender: news at newsbf01.news.aol.com> Message-ID: <3bgh5n$ol2 at newsbf01.news.aol.com>
> NNTP-Posting-Host: newsbf01.news.aol.com
>> My question is if someone can lead me to a review article, or an
> ariticle about this subject? Is it possible to take out the gene for
> anibody information and express that in bacteria or other micro-organism?
>>
Yes, check MEDLINE for recombinant Ab. gene coded for specific Ab can be
isolated either from hybridoma of Bcell or just Bcell.
Or you can produce Ab-like protein using gene coded for antigen-receptor from
macrophages and Tcell (isolated by solid phase-affinity traping) without
immunizing the animal.
