Michelle Epstein (mepstein at helix.nih.gov) wrote:
: I think that the greatest discovery in the last 25 years in immunology
: has to be monoclonal antibodies. It may not be as elegant and
: theoretically based but is one of the most important discoveries for
: immunology and many other biological disciplines.
: On 26 Oct 1994, Ephraim Fuchs wrote:
: > I would like to know what people think is the greatest advance in
: > immunology in the last 25 years. My opinion is that it is the two signal
: > model of lymphocyte activation, first proposed by David Dresser, then Don
: > Forsdyke (if I'm not mistaken, he is the founder of this usenet group),
: > then championed by Peter Bretscher and Mel Cohn and, for T cells, by
: > Kevin Lafferty and Alistair Cunningham. A distant second would be the
: > discovery of MHC restriction of T cell responses by Peter Doherty and
: > Rolf Zinkernagel.
: >
: >
: >
: >
The discovery and research into how MHC works is one of the most
interesting topics in immunology today if not one of the greatest
achievements. (by many of course).
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* Ken Hoekstra (veterinary technician) B.Sc hoekstra at unixg.ubc.ca *
* University of British Columbia Ken.Hoekstra at deepcove.com*
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