Jonathan Sprent in Paul, Ch.3, writes that it's an open question whether
TcR has two adjacent binding sites: one for self MHC and one for foreign
peptide or has one binding site for MHC+peptide complex. Diagrams in
Benjamin & Leskowitz (1993), in Paul (1993) ch. 1, and Sprent in Paul,
Ch.3, all seem to accept the second view. Comments? Mark Hodes
(markhodes at aol.com)
