In article <36b7jd$4l4 at agate.berkeley.edu>,
Ken Frauwirth (BioKen) <frauwirt at notmendel.Berkeley.EDU> wrote:
>Addressing the clustering of Class I and Class II MHC:
>>This is probably due less to the "need for diversity" than to the
>likelihood that the Class I and Class II genes probably arose from gene
>duplication, so they started out clustered.
>
Yet, duplications of other gene families have been found to be
distributed across multiple chromosomes. So, you're right, gene dupli-
cation events may tend to be "local" at first. The question then would
be why the MHC locus "hung together."
--
Unique ID : Ladasky, John Joseph Jr.
Title : BA Biochemistry, U.C. Berkeley, 1989
Location : Stanford University Dept. of Cell Biology, Fairchild D-105
Keywords : immunology, music, running, Green
