Hi,
I am urgently seeking an anti HLA-B18 monoclonal antibody. I need
this reagent to precipitate large quantities of HLA-B18 from cell
lysates that also contain HLA-A2, HLA-B70, HLA-C, and class II
molecules. In other words, I can use antibodies with cross-reactivities
that do not include class II, A2, B70, and C. Because I would like to
use Protein-A-matrix in the precipitation, an IgG2 would be preferred,
but I would like to know about any other subclasses which might be
available. I have tried anti-B18 serum for this precipitation without
success, therefore I now need to find an appropriate monoclonal.
Any help or advice is greatly appreciated!
Mark Luscher
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Dept. Immunology
University of Toronto