IUBio

Antibodies to murine dendritic cells

M. Doherty M_Doherty at NIH.gov
Fri Jul 7 09:50:08 EST 1995


In article <3thqg0$co1 at synapse.bms.com>, Lieping Chen
<LIEPING_CHEN at CCMAIL.BMS.COM> wrote:

> We are looking for monoclonal antibodies (other than 33D1 and N418) 
> specific for mouse dendritic cells.  Any info will be greatly 
> appreciated! 

You might like to try NLDC 145.  Original reference is:

Kraal, G. M., Breel, M., Janse, M. and Bruin, G. (1986).  Langerhans
cells, veiled cells and interdigitating cells in the mouse recognised by a
monoclonal antibody.  J. Exp. Med. 163, 981.

It stains dendritic cells well, and in our hands it was very good at
separating DC from atypical Mac-1-bright N418-dull macrophage-like cells.


Cheers, Mark



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