IUBio

Cleavage of MHC class II by trypsin

Kim Sabelko ksabelko at PHARMDEC.WUSTL.EDU
Mon Jul 31 13:44:55 EST 1995


Netters,

Does anyone know if trypsin can cleave MHC class II molecule off of cell
membranes.  
I am trypsinising my adherent APC to get them off the plate and I wonder if
trypsin affects class II at all.  Please help.

Thanks.
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Kimberly Sabelko                                  
Washington University School of Medicine
Molecular Biology and Pharmacology, Box 8103
660 S. Euclid Ave, Box 8103
St. Louis, MO  63110    (USA)                 

INTERNET:  ksabelko at pharmdec.wustl.edu
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