In article <00991D60.3A2E2920 at vms.csd.mu.edu>, 5431kumarv at vms.csd.mu.edu wrote:
> Hello. Could anyone please comment on the underlying importance of GPIV
> and the consequences (or benefits) of its absence?
There is much debate, and some readers of this group have more insights
than I. However, just from the platelet point of view it appears to be
involved in the second wave of aggregation, and auto-antibodies to GPIV
(or CD36 as it is also called) may mediate different types of
thrombocytopenia.
Most studies show no gross hematopathological characteristic associated
with the NAK A- (no GPIV) trait. That doesn't mean there isn't one, just
that it isn't clear from the few patients that have presented with the
trait.
Other opinions from readers of this newsgroup?
>> Also -- does anyone know of any studies which have shown any Caucasians
> who lack GPIV?
I haven't seen any. If anyone has, can they post it to this newsgroup?
>> Please send all responses to: giri at solaria.sol.net>> Thank you very much, in advance.
>> --Giridhar.
--
Beatrice Beaubien
Allelix Biopharmaceuticals Inc.
6850 Goreway Drive
Mississauga, Ontario
CANADA M4T 1S4
PHONE: 905.677.0831
FAX: 905.677.9595
