Try measuring total RNA. It is very cheap and could be used in the "third
world". All you need is a bottle of NaOH, a bottle of perchloric acid and
access to a uv spectrophotometer (hmmm. not so cheap!). The reference is
Biochem. J (1967) 105: 679 "Quantitative nucleic acid changes during PHA-
induced lymphocyte transformation in vitro."
Sincerely,
Don Forsdyke,
Discussion Leader. Bionet.Immunol.