In <189 at gigilamesh.win-uk.net> ndharper at gigilamesh.win-uk.net (Nick
Harper) writes:
>>Hi,
>>Can anyone out there tell me if there are specific CD markers to
>differentiate Th1 and Th2 CD4+ cells. Also are there specific
>determinants to distinguish CD8+ Ts and Tc cells?
>>thanks
>>Nick
>As I understand, Th1 and Th2 can be distinguished only by the pattern
of cytokines they secrete; there are no specific differentiation
markers. As far as "Ts" cells go, their existence as a discrete
sub-population remains controversial. CD4+ Th2 cells, for example can
be considered to have T "suppressor" acvitity as the cytokines they
secrete supress Th1 cells....So, the answer to both questions would be
no.
Monica Ranes-Goldberg
Immunology Instructor
UC Berkeley Extension
