In article <dward.3.2FAFAE31 at magnus.acs.ohio-state.edu>,
dward at magnus.acs.ohio-state.edu (Darrell E. Ward) writes:
> I would like to learn the meaning of the term "cluster designation", as in
> CD4.
This system is a method of identifying particular antigens on the surface of a
cell. For most of these antigens, several monoclonal antibodies have been
developed which recognise the same antigen. Since each antibody had a
different name this rapidly became confusing. Now there is an annual workshop
at which new monoclonal antibodies are examined and assigned either to an old
or new CD, depending on the specificity obviously. The results of this
workshop are published in various journals including Blood. There is a program
called LDAD available from the NIH which is quite useful for this.
Hope this helps.
Ian Davis davis at licre.ludwig.edu.au
